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Intramitochondrial serine protease activity of Omi/HtrA2 is required for caspase-independent cell death of human neutrophils

โœ Scribed by Zervos, A S; Roos, D; Kuijpers, T W; Blink, E; Maianski, N A; Alnemri, E S


Book ID
110016727
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
131 KB
Volume
11
Category
Article
ISSN
1350-9047

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## Abstract Protein phosphatase (PP) activity is associated with the regulation of apoptosis in neutrophils. However, the underlying regulatory mechanism(s) in apoptosis remain unclear. The type of cell death induced by okadaic acid (OA), the inhibitor of PP1 and PP2A, is characterized by apoptotic