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Intramitochondrial and Extramitochondrial Concentrations of Adenine Nucleotides and Inorganic Phosphate in Isolated Hepatocytes from Fasted Rats

✍ Scribed by Theodorus P. M. AKERBOOM; Hans BOOKELMAN; Peter F. ZUURENDONK; Roelof van der MEER; Joseph M. TAGER

Book ID
115116559
Publisher
John Wiley and Sons
Year
1978
Tongue
English
Weight
791 KB
Volume
84
Category
Article
ISSN
1432-1327

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πŸ“œ SIMILAR VOLUMES

Interaction of homogeneous mitochondrial
Interaction of homogeneous mitochondrial ATPase from rat liver with adenine nucleotides and inorganic phosphate
✍ Pedersen, Peter L. πŸ“‚ Article πŸ“… 1975 πŸ› Wiley (John Wiley & Sons) 🌐 English βš– 480 KB

## Abstract Mitochondrial ATPase from rat liver mitochondria contains multiple nucleotide binding sites. At low concentrations ADP binds with high affinity (1 mole/mole ATPase, K~D~ = 1–2 ΞΌM). At high concentrations, ADP inhibits ATP hydrolysis presumably by competing with ATP for the active site (