Ki-ras mutations in spontaneous and chem
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Hiroko Ohgaki; Paul Kleihues; Gordon C. Hard
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Article
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1991
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John Wiley and Sons
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English
โ 501 KB
A high frequency of point mutations at codon 12 of the Ki-ras gene has previously been reported for rat kidney mesenchymal tumors induced by methylating N-nitroso compounds. In this study, we analyzed renal tumors with divergent histogenesis, i.e., mesenchymal tumors (sarcomas), cortical epithelial