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Intragenic suppression: Stalker, a retrovirus-like transposable element, can compensate for a deficiency at thecutlocus ofDrosophila melanogaster

✍ Scribed by V. A. Mogila; A. B. Ladvishenko; O. B. Simonova; T. I. Gerasimova


Publisher
Springer Netherlands
Year
1992
Tongue
English
Weight
1000 KB
Volume
86
Category
Article
ISSN
0016-6707

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✦ Synopsis


A number of mutations at the cut locus were induced by non-precise exision of a silent P-element insertion which resulted in deletions at the regulatory region of the locus. Unexpectedly, a reversion of one of these mutations was found, which appears as a result of insertion of Stalker (a retrovirus-like mobile element) near the 1.3 kb deletion. Thus an insertion of a retrovirus-like mobile element can suppress the deficiency at the regulatory region of a gene.