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Intrafamilial transmission of Epstein-Barr virus infections

✍ Scribed by Gary R. Fleisher; Patrick S. Pasquariello; W. Stuart Warren; William S. Zavod; Arnold B. Korval; H. Dixon Turner; Evelyne T. Lennette

Book ID
119458931
Publisher
Elsevier Science
Year
1981
Tongue
English
Weight
327 KB
Volume
98
Category
Article
ISSN
1097-6833

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HE Epstein-Barr virus (EBV) was discovered 36 years ago by electron microscopy of cells cultured from Burkitt's lymphoma tissue by Epstein, Achong, and Barr. 1 Four years later, in 1968, EBV was shown to be the etiologic agent of heterophile-positive infectious mononucleosis. 2 EBV DNA was detected

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## Abstract Specific viral laboratory diagnosis of primary Epstein–Barr Virus (EBV) infection is usually based on antibody‐detection assays. During acute, lytic phase of infection, viral DNA can also be detected in serum. In the present study, the diagnostic utility of EBV DNA detection and quantit