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Intraendosomal degradation of transforming growth factor alpha

โœ Scribed by Frederick G Hamel; Gerri L Siford; June Jones; William C Duckworth


Book ID
117463656
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
461 KB
Volume
126
Category
Article
ISSN
0303-7207

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Transforming growth factor-alpha (TGFโฃ) is an epidermal growth factor receptor (EGFR) ligand which is distinguished from EGF by its acid-labile structure and potent transforming function. We recently reported that TGFโฃ induces less efficient EGFR heterodimerization and downregulation than does EGF (