Intraductal carcinoma of major salivary gland

✍ Scribed by Crawford Anderson; Richard Muller; Robert Piorkowski; David R. Knibbs; Paul Vignoti

• Publisher: John Wiley and Sons
• Year: 1992
• Tongue: English
• Weight: 893 KB
• Volume: 69
• Category: Article
• ISSN: 0008-543X
• DOI: 10.1002/1097-0142(19920201)69:3<609::aid-cncr2820690302>3.0.co;2-1

✦ Synopsis

The clinicopathologic features of the cases of three patients with intraductal carcinoma of major salivary gland are described. As in the breast, these lesions of salivary ducts appear to represent an in situ or preinvasive phase of the disease. On follow-up, one patient had a local recurrence, and in another patient, the tumor subsequently became invasive. This experience suggests that wide surgical excision [preferably total parotidectomy) may be curative but that resections limited to grossly visible disease will result in local recurrence and/or the development of invasive ductal adenocarcinoma. Cancer 1992; 69609-614.

Salivary duct carcinoma is a recently recognized neoplasm, so designated because of a striking histologic resemblance to ductal carcinoma of the breast.' As in the breast, an intraductal component may be identified.'-' We describe the clinicopathologic features of the cases of three patients that were noteworthy because they presented initially with intraductal carcinoma with no invasive component.