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Intradermal photosensitisation facilitates stimulation of MHC class-I restricted CD8 T-cell responses of co-administered antigen

✍ Scribed by Håkerud, Monika; Waeckerle-Men, Ying; Selbo, Pål Kristian; Kündig, Thomas M.; Høgset, Anders; Johansen, Pål


Book ID
121455795
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
740 KB
Volume
174
Category
Article
ISSN
0168-3659

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## Abstract We recently showed that MGL2 specifically binds tumour‐associated glycan __N__‐acetylgalactosamine (GalNAc). We here demonstrate that modification of an antigen with tumour‐associated glycan GalNAc, targets antigen specifically to the MGL2 on bone marrow derived (BM)‐DCs and splenic DCs