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Intracranial Pressure Observations in a Canine Model of Acute Liver Failure Supported by a Bioartificial Liver Support System

โœ Scribed by John F. Patzer II; Roberto C. Lopez; Shushma Aggarwal


Book ID
109093303
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
171 KB
Volume
31
Category
Article
ISSN
0160-564X

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Iron chelation attenuates intracranial p
โœ Nikolaos Arkadopoulos; Demetrios Vlahakos; Georgia Kostopanagiotou; Dimitrios Pa ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 250 KB

Oxidative mechanisms have been implicated in the pathogenesis of brain edema in acute liver failure (ALF). The aim of this study was to test the hypothesis that inhibition of iron-catalyzed oxidative reactions through iron chelation using deferoxamine could attenuate brain edema in a swine model of