Intracortical inhibition is reduced in a patient with a lesion in the posterolateral thalamus

✍ Scribed by Alexander Münchau; Michael Orth; John C. Rothwell; Vincenzo Di Lazzaro; Antonio Oliviero; Paolo Profice; Pietro Tonali; Peter P. Pramstaller; Kailash P. Bhatia

• Publisher: John Wiley and Sons
• Year: 2001
• Tongue: English
• Weight: 511 KB
• Volume: 17
• Category: Article
• ISSN: 0885-3185
• DOI: 10.1002/mds.1264

✦ Synopsis

Abstract

We describe a patient who developed a complex movement disorder following an ischemic lesion in the right posterolateral thalamus. Transcranial magnetic stimulation showed a shortening of the cortical silent period and deficient cortico‐cortical inhibition using paired magnetic pulses on the affected side, indicating reduced effectiveness of intracortical inhibitory mechanisms. © 2001 Movement Disorder Society.