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Intracerebroventricular injection of pipecolic acid inhibits food intake and induces sleeping-like behaviors in the neonatal chick

✍ Scribed by Tomo Takagi; Ryuichi Ando; Atsushi Ohgushi; Tomoe Yamashita; Eriko Dobashi; Hazizul Hussain-Yusuf; Ryoji Onodera; Takashi Bungo; Hiroyuki Sato; Mitsuhiro Furuse


Book ID
117471980
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
235 KB
Volume
310
Category
Article
ISSN
0304-3940

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Intracerebroventricular administration o
✍ T. Takagi; T. Bungo; T. Tachibana; E-S. Saito; S. Saito; I. Yamasaki; S. Tomonag πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 110 KB

## Abstract It has been demonstrated that L‐pipecolic acid (L‐PA), a major metabolic intermediate of L‐lysine (L‐Lys) in the mammalian and chicken brain, is involved in the functioning of the GABAergic system. A previous study has shown that intracerebroventricular (i.c.v.) injection of L‐PA suppre