Intracerebroventricular Administration of Ouabain to Rats Changes the Expression of NMDA Receptor Subunits in Cerebral Cortex and Hippocampus
✍ Scribed by María Geraldina Bersier; Georgina Rodríguez de Lores Arnaiz
- Publisher
- Springer
- Year
- 2009
- Tongue
- English
- Weight
- 385 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0364-3190
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## Abstract The expression of NMDA receptor NR1 subunit mRNA was studied in rat auditory cortex (AC) on different postnatal days using digoxigenin‐labeled oligonucleotide probes. The results showed that NR1expression increased from birth to postnatal day 35 (P35) and remained constant until P56. Th
Quantitative reverse transcriptase -polymerase chain reaction was used to analyze the relative expressions of NR1, NR2A, NR2B, NR2C, NR2D, and NR3 subunits of the NMDA receptor in the piriform, entorhinal, visual, and motor cortices as well as in the olfactory bulb of adult rat. The analysis detecte