Intracellular trafficking of LET-756, a fibroblast growth factor of C. elegans, is controlled by a balance of export and nuclear signals

Nuclear localization of basic fibroblast

Nuclear localization of basic fibroblast growth factor is mediated by heparan sulfate proteoglycans through protein kinase C signaling

✍ Edward Hsia; Thomas P. Richardson; Matthew A. Nugent 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 186 KB

## Abstract Understanding the process of wound healing will provide valuable insight for the development of new strategies to treat diseases associated with improper regeneration, such as blindness induced by corneal scarring. Heparan sulfate proteoglycans (HSPG) are not normally expressed in the c