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Intracellular trafficking of CLN3, the protein underlying the childhood neurodegenerative disease, Batten disease

✍ Scribed by Qinwen Mao; Haibin Xia; Beverly L Davidson

Book ID: 117106024
Publisher: Elsevier Science
Year: 2003
Tongue: English
Weight: 321 KB
Volume: 555
Category: Article
ISSN: 0014-5793
DOI: 10.1016/s0014-5793(03)01274-2

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## Abstract Batten disease, an inherited neurodegenerative storage disease affecting children, results from the autosomal recessive inheritance of mutations in __Cln3__. The function of the CLN3 protein remains unknown. A key to understanding the pathology of this devastating disease will be to elu