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Intracellular signaling pathways involved in post-mitotic dopaminergic PC12 cell death induced by 6-hydroxydopamine

✍ Scribed by Jezabel Rodriguez-Blanco; Vanesa Martín; Federico Herrera; Guillermo García-Santos; Isaac Antolín; Carmen Rodriguez


Book ID
111181050
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
541 KB
Volume
107
Category
Article
ISSN
0022-3042

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Activation of proteolytic enzymes, including the caspase family of proteinases, is a feature characteristic of the apoptotic program. In the present study, we examined a potential role of intracellular proteinases in the death of neuronal PC12 and primary cultured rat microglial cells induced by 6-h