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Intracellular signal transduction pathways mediating the anti-apoptotic action of gastrin

✍ Scribed by Andrea Todisco; Saravanan Ramamoorthy; Thomas Witham; Vinzenz Stepan; Nonthalee Pausawasdi


Book ID
119425566
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
189 KB
Volume
118
Category
Article
ISSN
0016-5085

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Adrenomedullin (ADM) plays an important role in the regulation of osteoblastic cells through both a proliferative and an anti-apoptotic effects. The present study investigated mechanisms involved in the effect of ADM on survival. We report that ADM can act in osteoblasts both through a non-transcrip