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Intracellular regulation of inward rectifier K+channels

✍ Scribed by J.P. Ruppersberg

Publisher
Springer
Year
2000
Tongue
English
Weight
232 KB
Volume
441
Category
Article
ISSN
0031-6768

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The effect of intracellular protons (Hi +) on the inward rectifier K + channel of the guinea-pig ventricular ceil membrane was examined, using the patch-clamp technique. The inward single-channel current was recorded in "inside-out" and "outside-out" patch configurations, while the pH of the solutio

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The effects of intracellular pH on an inwardly rectifying K + channel ("Kin channel") in opossum kidney (OK) cells were examined using the patch-clamp technique. Experiments with inside-out patches were first carried out in Mg 2+-and adenosine triphosphate (ATP)-free conditions, where Mg2+-induced i