## Abstract Substitution of NH~3~ by a range of amines in __trans__β[PtCl~2~(NH~3~)~2~] produces compounds with cytotoxicity significantly improved over the parent transplatin and in many cases equivalent to that of cisplatin. This microreview summarizes the chemistry and biology of __trans__βplati
Intracellular reactions of platinum antitumor compounds
β Scribed by J. Reedijk; E.L.M. Lempers; A.F. Struik; N. Boogaard
- Book ID
- 103567865
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- English
- Weight
- 78 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0162-0134
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
In a study of the biochemical mechanism of renal toxicity of certain antitumor platinum compounds, particularly cis-dichlorodiimineplatinum(II) @4X-119875), qualitative and quantitative studies of the soluble nonspecific kidney esterases were carried out using (C57BL/6 X DBA/Z) mice. There was a maj