Intracellular production of IL-2, IL-4, IFN-γ, and TNF-α by peripheral blood CD3+and CD4+T cells in children with atopic dermatitis
✍ Scribed by Edyta Machura; Bogdan Mazur; Jarosław Kwiecień; Krystyna Karczewska
- Publisher
- Springer
- Year
- 2006
- Tongue
- English
- Weight
- 254 KB
- Volume
- 166
- Category
- Article
- ISSN
- 0340-6997
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📜 SIMILAR VOLUMES
## Background: A number of studies exist demonstrating the increased expression of type 2 cytokines and decreased capacity to produce interferon-gamma (ifn-gamma) in peripheral blood mononuclear cells (pbmcs) of patients with atopic dermatitis (ad). ## Objectives: To clarify the results of recent
T cell clones are classified as type 0, 1 or 2 depending on the lymphokines they produce. However, it has remained unclear whether single cells of a given type produce one or several cytokine species. Flow cytometric analysis of peripheral blood lymphocytes (PBL) obtained from 20 healthy donors for