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INTRACELLULAR INTERLEUKIN-1 RECEPTOR ANTAGONIST TYPE I (ICIL-1RA1) MODULATES THE REPLICATIVE CAPACITY OF HUMAN ENDOTHELIAL CELLS

✍ Scribed by Rachael Dewberry; David Crossman; Sheila Francis


Book ID
116342121
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
42 KB
Volume
13
Category
Article
ISSN
1054-8807

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## Abstract Endothelial cells (EC) are very responsive to the proinflammatory cytokine inter‐leukin‐1 (IL‐1). EC are induced by IL‐1 to secrete chemotactic factors and to increase expression of cell surface adhesion molecules leading to increased leukocyte adhesion. Activated EC turther contribute