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Intracellular inhibitors of cysteine cathepsins in activated macrophages

✍ Scribed by Katarina Maher; Špela Konjar; Slavko Čeru; Matthew Bogyo; Boris Turk; Nataša Kopitar-Jerala

Book ID
116398911
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
44 KB
Volume
48
Category
Article
ISSN
1043-4666

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✍ Dr. J. Martel-Pelletier; J. M. Cloutier; J. P. Pelletier 📂 Article 📅 1990 🏛 Elsevier Science 🌐 English ⚖ 896 KB

## Abstract The aim of this study was to determine the involvement of cathepsin B and its inhibitors in the proteolytic degradation of human osteoarthritic (OA) tissue. The characteristics of the cathepsin B found in both normal and OA cartilage and synovium were similar to those of the lysosomal c