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Intracellular glutathione in human hepatocytes incubated with S-adenosyl-L-methionine and GSH-depleting drugs

✍ Scribed by Xavier Ponsoda; Ramiro Jover; María José Gómez-Lechón; Ricardo Fabra; Ramón Trullenque; JoséV. Castell


Book ID
103657212
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
594 KB
Volume
70
Category
Article
ISSN
0300-483X

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✍ Carmen García-Ruiz; Albert Morales; Anna Colell; Antonio Ballesta; Joan Rodés; N 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 931 KB

Mitochondrial glutathione plays an important role in maintaining a functionally competent organelle. Previous studies have shown that ethanol feeding selectively depletes the mitochondrial glutathione pool, more predominantly in mitochondria from perivenous hepatocytes. Because S-adenosyl-L-methioni