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Intracellular esterase activity of Candida albicans and its correlation with pathogenicity in mice

✍ Scribed by A.R. Khosravi; M. Riazipour; H. Shokri; M. Mousavi

Publisher
Masson Editeur
Year
2008
Tongue
French
Weight
319 KB
Volume
18
Category
Article
ISSN
1156-5233

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✦ Synopsis

Objective. -To determine the virulence of clinical Candida albicans isolates and intracellular esterase activity in differentiating the virulent strains. Materials and methods. -The virulence of 17 isolates of C. albicans was determined in BALB/c mice with Candidiasis. The esterase activity against five substrates was assayed by a colorimetric method.

Results. -The results showed that the virulence of C. albicans isolates was considerably different from each other. The esterase activity against each of the five substrates did not show significant correlation with the virulence of the isolates. Comparison of the mean esterase activity of the human and animal isolates showed significant differences against some of the substrates.

Conclusion. -It is concluded that this study showed a positive but not significant correlation between some intracellular esterase activities and the C. albicans virulence.

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