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Intracellular DNA recognition

✍ Scribed by Hornung, Veit; Latz, Eicke

Book ID: 109956240
Publisher: Nature Publishing Group
Year: 2010
Tongue: English
Weight: 484 KB
Volume: 10
Category: Article
ISSN: 1474-1741
DOI: 10.1038/nri2690

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Several general principles emerge from the studies of Cro, lambda repressor, and CAP. The DNA-binding sites are recognized in a form similar to B-DNA. They do not form cruciforms or other novel DNA structures. There seem to be proteins that bind left-handed Z-DNA (87) and DNA in other conformations,