โ Scribed by Ming Zhao; Ralph Weissleder
No coin nor oath required. For personal study only.
Efficient delivery of therapeutic and diagnostic agents across the plasma membrane is crucial in developing novel therapies. Membrane permeating peptides, in particular HIVโ1 tat peptide and its derivatives, have enabled the intracellular delivery of cargos of various sizes and physicochemical properties. This review summarizes the current knowledge of tatโderived cell permeating peptides in the transduction of exogenous molecules/complexes. ยฉ 2003 Wiley Periodicals, Inc. Med Res Rev, 24, No. 1, 1โ12, 2004
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