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Intracellular cAMP in Dictyostelium discoideum: Characterization of an aggregation-deficient mutant with elevated cAMP pools

✍ Scribed by Chan, Fred K. ;Coukell, M. Barrie


Publisher
John Wiley and Sons
Year
1981
Tongue
English
Weight
934 KB
Volume
2
Category
Article
ISSN
0192-253X

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## Abstract To find mutants of Dictyostelium discoideum that are unable to respond to exogenous cAMP signals (frigid mutants), amoebae of 218 independent aggregation‐deficient mutants were treated in suspension with artificial pulses of cAMP and screened for the capacity to form EDTA‐resistant cohe