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Intracellular ATP directly blocks K+ channels in pancreatic B-cells

✍ Scribed by Cook, Daniel L.; Hales, Nicholas


Book ID
109736616
Publisher
Nature Publishing Group
Year
1984
Tongue
English
Weight
347 KB
Volume
311
Category
Article
ISSN
0028-0836

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The resting conductance of cultured ]?-cells from murine pancreases was investigated using the whole-cell, cell-attached and isolated patch modes of the patch-clamp technique. Whole-cell experiments revealed a high input resistance of the cells (>20 GO per cell or > 100 kg? -cm2), if the medium dial