✦ LIBER ✦

Intracavitary radiation in the treatment of advanced esophageal carcinoma: A comparison of high dose rate vs. low dose rate brachytherapy

✍ Scribed by James C. Harvey; Erik H. Fleischman; John E. Bellotti; A. Robert Kagan

Publisher: John Wiley and Sons
Year: 1993
Tongue: English
Weight: 317 KB
Volume: 52
Category: Article
ISSN: 0022-4790
DOI: 10.1002/jso.2930520209

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Twenty‐two patients were irradiated using two different dose schedules of intracavitary irradiation for palliation of locally advanced or metastatic carcinoma of the esophagus. Irradiation was given solely with either manually afterloaded low/Intermediate dose Cesium‐137 (LDR) or high dose rate Iridium‐192 (HDR) delivered via remote afterloader. This study was designed to test the effectiveness of HDR intracavitary brachytherapy in the relief of dysphagia and the maintenance of esophageal patency and to compare with our previous experiences with LDR intracavitary brachytherapy. Accelerated treatments were especially suited for patients with poor physical condition or short life expectancy unlikely to complete a full course of external beam irradiation without treatment interruption. Two thousand cGY in three fractions of LDR was compared with 1,250 cGY in one fraction HDR with essentially equal results. © 1993 Wiley‐Liss, Inc.

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