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Intracavernous injection of vasoactive drugs in the rabbit

โœ Scribed by Stackl, W. ;Loupal, G. ;Holzmann, A.


Book ID
104701520
Publisher
Springer
Year
1988
Tongue
English
Weight
355 KB
Volume
16
Category
Article
ISSN
0300-5623

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โœฆ Synopsis


To investigate the erectile response and side effects of intracavernous injection of vasoactive agents, 7 groups of 5 rabbits each underwent injection of either isotonic saline or 1 of 6 drugs. Phentolamine most consistently produced full erection with few inflammatory reactions, while phenoxybenzamine produced erection but also severe inflammation and sclerosis of the corpus cavernosum. With prostaglandin E1, neither erection nor inflammation was observed.


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