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Intra-CNS activation by antigen-specific T lymphocytes in experimental autoimmune encephalomyelitis

โœ Scribed by Saad Muhallab; Olle Lidman; Robert Weissert; Tomas Olsson; Anders Svenningsson

Book ID
114137290
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
549 KB
Volume
113
Category
Article
ISSN
0165-5728

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## Abstract Self antigens bind to MHC class II molecules __in vivo__. The capacity of class II molecules to bind native self antigen, namely antigen that has not been processed through an endososomal pathway, could increase susceptibility to autoimmune diseases if recognized by autoreactive T lymph