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Intra-arterial continuous infusion of cis-diamminedichloroplatinum in untreated head and neck cancer patients

✍ Scribed by Sergio Frustaci; Luigi Barzan; Salvatore Tumolo; Roberto Comoretto; Giovanni Quadu; Enzo Galligioni; Manlio Lorenzini; Diana Crivellari; Giuseppe Caruso; Giampaolo Piccinin; Andrea Veronesi; Umberto Tirelli; Eligio Grigoletto


Publisher
John Wiley and Sons
Year
1986
Tongue
English
Weight
643 KB
Volume
57
Category
Article
ISSN
0008-543X

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Concomitant radiation therapy and cis-di
✍ Creagan, Edward T. ;Fountain, Karen S. ;Frytak, Stephen ;Desanto, Lawrence W. ;E πŸ“‚ Article πŸ“… 1981 πŸ› John Wiley and Sons 🌐 English βš– 133 KB πŸ‘ 1 views

## Abstract Three patients with locally advanced head and neck squamous cell cancer received concomitant radiation therapy (XRT) and cis‐diamminedichloroplatinum (CDDP). The dose of 6,000 rads was to be administered in two 3,000‐rad courses separated by 3 weeks. The CDDP, 30 mg/m^2^, was to be give

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## Abstract A 65‐year‐old man with squamous cell carcinoma of the head and neck was initially treated with radiation therapy and systemic chemotherapy resulting in a complete remission. Recurring tumor, 2Β½ years later, caused advanced destruction of most left hemi‐face tissues. Intraarterial infusi

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Twenty-eight patients with measurable or evaluable, regionally advanced or metastatic head and neck cancer received the combination of cyclophosphamide (C), adriamycin (ADR), and a 24-hour infusion of cisdiamminedichloroplatinum (11) (P). Most patients had received extensive prior surgery and radiat