Intra-arterial continuous infusion of cis-diamminedichloroplatinum in untreated head and neck cancer patients
β Scribed by Sergio Frustaci; Luigi Barzan; Salvatore Tumolo; Roberto Comoretto; Giovanni Quadu; Enzo Galligioni; Manlio Lorenzini; Diana Crivellari; Giuseppe Caruso; Giampaolo Piccinin; Andrea Veronesi; Umberto Tirelli; Eligio Grigoletto
- Publisher
- John Wiley and Sons
- Year
- 1986
- Tongue
- English
- Weight
- 643 KB
- Volume
- 57
- Category
- Article
- ISSN
- 0008-543X
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## Abstract Three patients with locally advanced head and neck squamous cell cancer received concomitant radiation therapy (XRT) and cisβdiamminedichloroplatinum (CDDP). The dose of 6,000 rads was to be administered in two 3,000βrad courses separated by 3 weeks. The CDDP, 30 mg/m^2^, was to be give
## Abstract A 65βyearβold man with squamous cell carcinoma of the head and neck was initially treated with radiation therapy and systemic chemotherapy resulting in a complete remission. Recurring tumor, 2Β½ years later, caused advanced destruction of most left hemiβface tissues. Intraarterial infusi
Twenty-eight patients with measurable or evaluable, regionally advanced or metastatic head and neck cancer received the combination of cyclophosphamide (C), adriamycin (ADR), and a 24-hour infusion of cisdiamminedichloroplatinum (11) (P). Most patients had received extensive prior surgery and radiat