Intestinal tissue kallikrein–kallistatin profile in inflammatory bowel disease
✍ Scribed by Antoni Stadnicki; Urszula Mazurek; Danuta Plewka; Tadeusz Wilczok
- Book ID
- 117798203
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 252 KB
- Volume
- 3
- Category
- Article
- ISSN
- 1567-5769
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Tissue kallikrein cleaves kininogens to release kinins. Kinins mediate inflammation by activating constitutive bradykinin receptor-2 (BR2), which are rapidly desensitized, and induced by inflammatory cytokines bradykinin receptor-1 (BR1), resistant to desensitization. Intestinal tissue kallikrein (
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