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Intestinal, segmented, filamentous bacteria

✍ Scribed by Klaasen, H

Book ID
122135901
Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
880 KB
Volume
88
Category
Article
ISSN
0378-1097

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A technique is described so that mice mono-associated with non-cultivable, segmented filamentous bacteria (SFB's) can be produced for the first time. As SFB donors, mice were used which had an intestinal microflora consisting of both SFB's and bacteria of the genus Clostridium. Recipients were germ-

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## Background: The aim was to analyze the influence of intestinal microbiota on the development of intestinal inflammation. We used the model of chronic inflammation that develops spontaneously in the colon of conventional severe combined immunodeficiency (SCID) mice restored with the CD45 RB high