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Intestinal secretagogues increase cytosolic free Ca2+concentration and K+conductance in a human intestinal epithelial cell line

✍ Scribed by Toshihiko Yada; Shigetoshi Oiki; Shunji Ueda; Yasunobu Okada


Publisher
Springer
Year
1989
Tongue
English
Weight
910 KB
Volume
112
Category
Article
ISSN
0022-2631

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Biphasic rises in cytosolic free Ca2+in
✍ Akihiro Hazama; Yasunobu Okada 📂 Article 📅 1990 🏛 Springer 🌐 English ⚖ 535 KB

During exposure to a hypotonic solution (55% osmolarity), cultured human epithelial (Intestine 407) cells exhibit a regulatory volume decrease after osmotic swelling. This process is known to involve parallel activation of volume-regulatory K + and C1-conductances. Biphasic increase in the cytosolic