Intestinal Lipid Metabolism

✍ Scribed by Henkjan J. Verkade, Patrick Tso (auth.), Charles M. Mansbach II, Patrick Tso, Arnis Kuksis (eds.)

• Publisher: Springer US
• Year: 2001
• Tongue: English
• Leaves: 443
• Edition: 1
• Category: Library

✦ Synopsis

This book was stimulated by the enthusiasm shown by attendees at the meetings in Saxon River, VT, sponsored by the Federation ofAmerican Societies for Experimental Biology (FASEB), on the subject of the intestinal processing of lipids. When these meetings were first started in 1990, the original organizers, two of whom are editors ofthis volume (CMM and PT), had two major goals. The first was to bring together a diverse group ofinvestiga­ tors who had the common goal of gaining a better understanding of how the intestine ab­ sorbs lipids. The second was to stimulate the interest of younger individuals whom we wished to recruit into what we believed was an exciting and fruitful area ofresearch. Since that time, the field has opened up considerably with new questions being asked and new an­ swers obtained, suggesting that our original goals for the meetings were being met. In the same spirit, it occurred to us that there has not been a recentbook that draws to­ gethermuch ofthe informationavailableconcerninghow the intestineprocesses lipids. This book is intended to reach investigators with an interest in this area and their pre- and post­ doctoral students. The chapters are written by individuals who have a long-term interest in the areas about which they write, and many have been speakers at the subsequent FASEB conferences that have followed on the first.

✦ Table of Contents

Front Matter....Pages i-xxii
Biophysics of Intestinal Luminal Lipids....Pages 1-18
Preduodenal Lipases and their Role in Lipid Digestion....Pages 19-35
Molecular Mechanisms of Pancreatic Lipase and Colipase....Pages 37-59
Pancreatic Lipase....Pages 61-79
Biology, Pathology, and Interfacial Enzymology of Pancreatic Phospholipase A 2 ....Pages 81-104
Enterostatin/Procolipase....Pages 105-118
Cholesterol Esterase....Pages 119-134
The Influence of the Intestinal Unstirred Water Layers on the Understanding of the Mechanisms of Lipid Absorption....Pages 135-152
The Role of Fatty Acid Binding Proteins in Enterocyte Fatty Acid Transport....Pages 153-170
Microsomal Triglyceride Transfer Protein....Pages 171-184
Intestinal Synthesis of Triacylglycerols....Pages 185-213
Triacylglycerol Movement in Enterocytes....Pages 215-233
Regulation of Intestinal Cholesterol Metabolism....Pages 235-262
Regulation of Intestinal Apolipoprotein Gene Expression....Pages 263-294
Recent Progress in the Study of Intestinal Apolipoprotein B Gene Expression....Pages 295-306
The Role of Apolipoprotein A-IV as a Satiety Factor....Pages 307-323
The Possible Role of Intestinal Surfactantlike Particles in the Absorption of Triacylglycerols in the Rat....Pages 325-334
Inhibitors of Chylomicron Formation and Secretion....Pages 335-349
Intestinal Absorption and Metabolism of Peroxidized Lipids....Pages 351-366
Intestinal Absorption of Fat-Soluble Vitamins....Pages 367-381
Intestinal Metabolism of Interesterified Fats....Pages 383-401
Structured Triacylglycerols in Clinical Nutrition....Pages 403-419
Back Matter....Pages 421-434

✦ Subjects

Biochemistry, general; Medical Biochemistry