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Intestinal epithelial cell signalling and chronic inflammation: From the proteome to specific molecular mechanisms

✍ Scribed by Tanja Werner; Dirk Haller


Book ID
113809070
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
867 KB
Volume
622
Category
Article
ISSN
0027-5107

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## Abstract Inflammation induces the NF‐κB dependent protein A20 in human renal proximal tubular epithelial cells (RPTEC), which secondarily contains inflammation by shutting down NF‐κB activation. We surmised that inducing A20 without engaging the pro‐inflammatory arm of NF‐κB could improve outcom