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Intestinal absorption of amino acid derivatives: Importance of the free α-amino group

✍ Scribed by G. L. Amidon; M. Chang; D. Fleisher; R. Allen


Publisher
John Wiley and Sons
Year
1982
Tongue
English
Weight
369 KB
Volume
71
Category
Article
ISSN
0022-3549

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Intestinal absorption of amino acid deri
✍ G. L. Amidon; M. Lee; H. Lee 📂 Article 📅 1983 🏛 John Wiley and Sons 🌐 English ⚖ 220 KB

The intestinal absorption of L-lysine-p-nitroanilide, L-alanine-p-nitroanilide, and glycine-p-nitroanilide was studied in perfused rat intestine in the presence of a variety of potential competitive inhibitors. The results indicate that the hydrolysis site(s) show side-chain specificity, and that in