## Abstract ## Objective Type IX collagen is an important component of the intervertebral disc extracellular matrix. Mutations in type IX collagen are associated with premature disc degeneration in mice and a predisposition to disc disorders in humans. The aim of this study was to assess the preva
Intervertebral disc degeneration in adult mice with hereditary kyphoscoliosis
โ Scribed by Dr. R. M. Mason; A. J. Palfrey
- Publisher
- Elsevier Science
- Year
- 1984
- Tongue
- English
- Weight
- 599 KB
- Volume
- 2
- Category
- Article
- ISSN
- 0736-0266
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## Abstract The purpose of this study is (1) to determine the correlation between __T__~1ฯ~ and __T__~2~ and degenerative grade in intervertebral discs using in vivo 3.0โT MRI, and (2) to determine the association between __T__~1ฯ~ and __T__~2~ and clinical findings as quantified by the SFโ36 Quest
The mechanical strength of connective tissues is dependent on the integrity of their fibrillar collagen frameworks. The objective of the present study was to assess type-II collagen damage (denaturation) in the adult human intervertebral disc compared with articular cartilage, in order to determine