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Interventional strategies against prion diseases

✍ Scribed by Aguzzi, Adriano; Glatzel, Markus; Montrasio, Fabio; Prinz, Marco; Heppner, Frank L.

Book ID
109775947
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
193 KB
Volume
2
Category
Article
ISSN
1471-0048

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## Abstract __Prion diseases are fatal neurodegenerative infectious disorders for which no therapeutic or prophylactic regimens exist. Understanding the molecular process of conformational conversion of the cellular prion protein (PrP__^__c__^__) into its pathological isoform (PrP__^__Sc__^__) will