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Interval carcinomas of the breast: A group with intermediate outcome

✍ Scribed by Schroën, Alma A.; Wobbes, Theo; van der Sluis, Rigtje F.


Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
400 KB
Volume
63
Category
Article
ISSN
0022-4790

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✦ Synopsis


Background: Interval carcinoma is defined as a carcinoma detected between two mammographic screening rounds after a negative screening. By some authors these carcinomas are considered to be more aggressive than screen-detected carcinomas.

Methods: In a group of 937 patients referred for breast cancer in the period [1975][1976][1977][1978][1979][1980][1981][1982][1983][1984][1985][1986][1987][1988][1989][1990]76 interval carcinoma patients were treated. In a retrospective study the outcome was studied of patients with an interval carcinoma in comparison with patients with screen-detected carcinomas and of patients with clinically detected carcinomas outside the screening program. Results: No significant difference was found in the 5-year and 10-year disease-free suhival of patients with interval carcinoma (80%, 68%) and the screen-detected group (89%, 81%) (P = 0.12). The interval group did significantly better than the patients with carcinomas detected outside the screening program ( P = 0.03).

Conclusion:

Interval-detected cancers for patients in the screening program had an outcome intermediate between patients with screen-detected cancers and patients with cancers detected outside the screening program. The difference between interval-detected cancers and cancers detected outside the screening program was significant, whereas the difference between screen-detected and interval cancers was not.


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