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Interstrand cross-links of cisplatin induce striking distortions in DNA

✍ Scribed by Jean-Marc Malinge; Marie-Josèphe Giraud-Panis; Marc Leng


Book ID
108405206
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
422 KB
Volume
77
Category
Article
ISSN
0162-0134

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Activation of Src, which has an intrinsic protein tyrosine kinase (PTK) activity, has been demonstrated in human solid tumors, such as colorectal and breast cancers. To investigate the role of activated Src in drug resistance, we evaluated the effect of v-src on the resistance to various anti-cancer