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Interstitial pneumonitis and venocclusive disease of the liver after bone marrow transplantation

โœ Scribed by Piedbois, P.; Ganem, G.; Cordonnier, C.; Levy, C.; Benk, V.; Pavlovitch, J.M.; Saint-Marc Giradin, M.F.; Kuentz, M.; Marinello, G.; Mazeron, J.J.; Dhumeaux, D.; Vemant, J.P.; Le Bourgeois, J.P.

Book ID
122170781
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
209 KB
Volume
18
Category
Article
ISSN
0167-8140

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Venocclusive disease (VOD) of the liver, a fibrous obliteration of small hepatic venules, can be caused by chemoradiation therapy. We reviewed 255 consecutive patients undergoing bone marrow transplantation for malignancy during 1978 to 1980 in order to determine the incidence of VOD and the predisp

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Hepatic venocclusive disease occurs with a spectrum of severity in an estimated 21 % of bone marrow transplant patients. Clinical features include severe right upper quadrant pain, ascites, weight gain and initially minimal derangement of liver function. In contrast to hepatic graft versus host dise