Interstitial brachytherapy and early tongue squamous cell carcinoma management

✍ Scribed by J. L. Lefebvre; B. Coche-Dequeant; B. Castelain; B. Prevost; E. Buisset; J. Ton Van

• Book ID: 102237499
• Publisher: John Wiley and Sons
• Year: 1990
• Tongue: English
• Weight: 417 KB
• Volume: 12
• Category: Article
• ISSN: 1043-3074
• DOI: 10.1002/hed.2880120307

✦ Synopsis

The results of treatment of 341 previously untreated patients with early squamous cell carcinoma (SCC) of the anterior two thirds of the tongue using iridium 192 implants (January 1974-December 1983) are presented. Furthermore, 265 patients underwent neck dissection, followed, in 102 cases, by radiotherapy. Incidence of local treatment complications was 19% (66 patients; however, only 3% (11 patients) needed more than a single medical treatment. Two months after completion of overall treatment, 326 patients (96%) were free of disease. Local failures occurred in 18% of cases; however, after successful salvage surgery this rate was reduced to 11%. Neck failures occurred in 18% of cases, but after successful salvage were reduced to 12%. Distant metastases were rare (1.5%), whereas metachronous cancers were frequent (1 02 patients). Survival rates were 61 % (56% to 66%) at 3 years, 46% (41% to 51%) at 5 years, and 26% (23% to 34%) at 10 years. Deaths due to tongue cancer evolution (20%) equalled those due to metachronous cancers (18.5%) and intercurrent diseases (21 %). HEAD & NECK 12~232-236,1990

O r a l tongue squamous cell carcinomas (SCCS) are frequent in Northern France. About 1,500 new head and neck cancers are recorded yearly