Phylogenetic relations among the three species in grain amaranth need investigation to provide information for breeding experiments germplasm conservation efforts, and decision on evolutionary patterns in the grain types . Hybrid development from crosses between species was studied to find out genetic relationship between them . Interspecific crosses were made among Amaranthus hypochondriacus, A . caudatus and A . cruentus in the glasshouse . The F t plants were relatively easy to obtain but had low pollen fertility (10 .3-15 .1%) and low seed set . A few of these hybrids did not produce seeds . Only a few Ft seeds obtained in crosses between A. cruentus and A . caudatus. All the Ft plants from these crosses died at the seedling stage . Crosses between A . cruentus and A . hypochondriacus produced few seeds . Most of the F t plants obtained from the seeds died at the seedling stage with only four plants growing to maturity but were sterile . Based on hybrid development, it was suggested that A . hypochondriacus and A. caudatus were genetically closer than the other two combinations of species studied . A . cruentus seemed to be genetically closer to A . hypochondriacus than it was to A. caudatus .