Interruption of mother-to-infant transmission of hepatitis B: time to include selective antiviral prophylaxis?
β Scribed by Geoffrey Dusheiko
- Book ID
- 117308992
- Publisher
- The Lancet
- Year
- 2012
- Tongue
- English
- Weight
- 56 KB
- Volume
- 379
- Category
- Article
- ISSN
- 0140-6736
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Hepatitis B virus (HBV) nucleotide sequences isolated from motherkhild pairs were analyzed in three cases of neonatal fulminant hepatitis B (FHB). Heterogeneous HBV sequences consistent with both adw2 and ayw subtype were found in all three mothers. In one case, in which the child survived, both sub
## Abstract Over 90% of infants infected with hepatitis B virus (HBV) caused by motherβtoβinfant transmission will evolve to carrier status, and this cannot be prevented until widespread administration of the HB vaccine and hepatitis B immune globulin (HBIG) is implemented. This prospective study o
Cellular immunity to HBcAg was studied in hepatitis B virus carrier children and neonates born to hepatitis B virus carrier mothers. A significant proliferative response of peripheral blood mononuclear cells to HBcAg was found in 5 of 10 children with elevated ALT levels but in none of the nine HBeA