Interrelationship between monoamine oxidase inhibition and central nervous system depressant activity of Substituted Quinazolone Hydrazides

Substituted benzoxazole/benzthiazole-2-t

Substituted benzoxazole/benzthiazole-2-thiones: Interrelationship between anticonvulsant activity and inhibition of nicotinamide adenine dinucleotide-dependent oxidations and monoamine oxidase

✍ Radhey S. Misra; Jayanti P. Barthwal; Surendra S. Parmar; Stanley J. Brumleve 📂 Article 📅 1974 🏛 John Wiley and Sons 🌐 English ⚖ 405 KB

0 3-Alkyl benzoate/benzhydrazide aminomethyl benzoxazole/benzthiazole-2-thiones were synthesized and evaluated for their ability to affect the respiratory activity of rat brain homogenate. All compounds were found to inhibit selectively the nicotinamide adenine dinucleotide (NAD)-dependent oxidation