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Interrelationship between Growth Factor-Induced pH Changes and Intracellular Ca2+

✍ Scribed by Harlan E. Ives and Thomas O. Daniel

Book ID: 123634221
Publisher: National Academy of Sciences
Year: 1987
Tongue: English
Weight: 986 KB
Volume: 84
Category: Article
ISSN: 0027-8424
DOI: 10.2307/29565

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## Abstract An increase in intracellular Ca^2+^ concentration ([Ca^2+^]~i~) may play a role in the proliferative effect of several growth factors. In this study, the changes in [Ca^2+^]~i~ elicited by epidermal growth factor (EGF) in rat cardiac microvascular endothelial cells (CMEC) have been inve