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Interrelationship between Diabetes and Homocysteine Metabolism: Hormonal Regulation of Cystathionine β-Synthase


Book ID
111777436
Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
156 KB
Volume
61
Category
Article
ISSN
0029-6643

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High homocysteine (HCY) levels are a risk factor for osteoporotic fracture. Furthermore, bone quality and strength are compromised by elevated HCY owing to its negative impact on collagen maturation. HCY is cleared by cystathionine b-synthase (CBS), the first enzyme in the transsulfuration pathway.