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Interrelationship among insulin, glucagon and somatostatin secretory responses to exendin-4 in the perfused rat pancreas

✍ Scribed by Ramona A. Silvestre; Jovita Rodrı́guez-Gallardo; Eva M. Egido; J. Marco

Book ID
114015636
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
320 KB
Volume
469
Category
Article
ISSN
0014-2999

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Difference in calcium dependency of insu
Difference in calcium dependency of insulin, glucagon and somatostatin secretion in response to glibenclamide in perfused rat pancreas
✍ S. Efendić; V. Grill; A. Nylén; C.-G. Östensson 📂 Article 📅 1982 🏛 Springer 🌐 English ⚖ 511 KB

The extracellular calcium requirements for insulin, glucagon and somatostatin release induced by 1 microgram/ml of glibenclamide have been compared in the perfused, isolated rat pancreas. In the absence of glucose, the drug evoked insulin release equally well at physiological (2.6 mmol/l) and low (0