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Interpreting the Clinical Significance of Capacity Scores for Informed Consent in Alzheimer Disease Clinical Trials

โœ Scribed by Karlawish, Jason; Kim, Scott Y.H.; Knopman, David; van Dyck, Christopher H.; James, Bryan D.; Marson, Daniel


Book ID
122422832
Publisher
American Psychiatric Publishing Inc
Year
2008
Tongue
English
Weight
92 KB
Volume
16
Category
Article
ISSN
1064-7481

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## Abstract ## Background A minimum 4โ€point change at 6 months on the Alzheimer's disease assessment scaleโ€cognitive subscale (ADASโ€cog) is deemed clinically important, but this cutโ€point has been little studied in relation to clinical meaningfulness. In an investigatorโ€initiated, clinical trial o